sesquiterpene lactone

カタログ番号	製品名	別名
T71553	Ainsliadimer A
	Ainsliadimer A, a sesquiterpene lactone dimer from Ainsliaea macrocephala, has antitumour activity and induces cell death in various cancer cells.
T32576	Laserolide
	Laserolide is a sesquiterpene lactone.
T32646	Leptocarpin
	Leptocarpin is a sesquiterpene lactone extracted from Leptocarpha rivularis.
T26546	Acantholide	NSC 277282,NSC-277282,NSC277282
	Acantholide is a Sesquiterpene lactone isolated from Acanthospermum glabratum.
T32766	Linifolin A	NSC 153859,NSC-153859,NSC153859,PF 57,PF-57
	Linifolin A is a sesquiterpene lactone extracted from Helenium aromaticum.
T32256	Janerin
	Janerin is a sesquiterpene lactone.
T32661	Leucanthanolide
	Leucanthanolide is a sesquiterpene lactone from Montanoa leucantha.
T34288	Repin
	Repin, a plant responsible for Parkinson-like disease in horses, is the principal sesquiterpene lactone extracted from Russian knapweed.
T69173	Ambrosin
	Ambrosin is a sesquiterpene lactone and a potent NF-κβ inhibitor. It is currently being studied as a potential lead drug for Alzheimer disease therapeutics.
T71925	Isonanangenine B
	Isonanangenine B is a drimane sesquiterpene lactone that has been found in Aspergillus. It decreases survivin mRNA expression in a reporter assay when used at concentrations of 13.6, 18.42, and 26.31 µM. Isonanagenine B ...

Compounds

Ainsliadimer A

T71553

Synonym: NSC 277282,NSC-277282,NSC277282

Target:

Linifolin A

T32766

Synonym: NSC 153859,NSC-153859,NSC153859,PF 57,PF-57

カタログ番号	製品名	別名	ターゲット
T9144	Telekin		Others
	Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells		Others
T8898	Granilin	Graniline	Others , Antibacterial , Antifungal
	Granilin (Graniline)e is a natural product.		Others , Antibacterial , Antifungal
TQ0234	Epoxymicheliolide	1β,10β-Epoxymicheliolide	Others
	Epoxymicheliolide (1β,10β-Epoxymicheliolide) is a novel guaiane-type sesquiterpene lactone isolated from Inula helenium L.		Others
TQ0096	Scabertopin		Others
	Scabertopin is a sesquiterpene lactone isolated from Gentiana scabra with anticancer and bacteriostatic activities.		Others
T5688	Micheliolide		NOS , NF-κB , COX
	Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.		NOS , NF-κB , COX
T2896	Alantolactone	helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor	Apoptosis , STAT , TGF-beta/Smad
	Alantolactone (Inula camphor)(Alant camphor), a sesquiterpene lactone, has potential activity against triple-negative breast Y MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3...		Apoptosis , STAT , TGF-beta/Smad
T5793	Britannin		Apoptosis , AMPK , Autophagy
	Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.		Apoptosis , AMPK , Autophagy
T2904	Sclareolide	Norambreinolide	Others , Antibacterial
	Sclareolide (Norambreinolide) is a sesquiterpene lactone natural product derived from various plant sources including Salvia yosgadensis, Salvia sclarea, and cigar tobacco. It is a close analog of Sclareol, a plant antif...		Others , Antibacterial
T13686	Ergolide		NF-κB
	Ergolide, a sesquiterpene lactone extracted from the dried flowers of Inula Britannica, effectively hinders the expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in RAW 264.7 macrophages by deactivating...		NF-κB
TN6735	Bigelovin		Apoptosis , Reactive Oxygen Species , Retinoid Receptor , Autophagy , RAR/RXR
	Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a pote...
TN1405	Arnicolide D		Akt , Caspase , PI3K , STAT , mTOR
	Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling path...		Akt , Caspase , PI3K , STAT , mTOR
T4672	Brevilin A		Apoptosis , Anti-infection , JAK , STAT , Autophagy
	Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT si...		Apoptosis , Anti-infection , JAK , STAT , Autophagy
TN3780	Deacetyleupaserrin		Others
	Deacetyleupaserrin is an antileukemic sesquiterpene lactone.		Others
T83442	17(13→14)-Abeo-ent-3S,13S,16-trihydroxystrob-8(15)-ene
	17(13→14)-Abeo-ent-3S,13S,16-trihydroxystrob-8(15)-ene is a sesquiterpene lactone of natural origin that exhibits anti-inflammatory properties [1].
T81167	Shizukanolide
	Shizukanolide, a sesquiterpene lactone extracted from Chloranthus japonicus (Chloranthaceae), has a dehydro derivative that exhibits moderate antifungal activity [1].
T15467	Helenalin		Others
	Helenalin is a selective inhibitor of transcription factor NF-κB by direct targeting of p65. It is an anti-inflammatory sesquiterpene lactone compound with alkylating activity. Through its ability to target the cysteine ...		Others
T83554	(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one
	(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one is a sesquiterpene lactone featuring a complex bicyclic structure [1].
T75678	Tomentosin		Apoptosis
	Tomentosin, a sesquiterpene lactone extracted from Caspian sea raspberry, has potential anti-inflammatory and anticancer activities, promoting apoptosis and inhibiting proliferation, migration and invasion of pancreatic ...		Apoptosis
T80956	Transilin
	Transilin, a sesquiterpene lactone, can be isolated from the entire Lepisorus contortus (Christ) Ching plant [1].